Pittsburgh Police from Zone 2 responded for a Shotspotter alert for a single shot fired in the 2100 block of Wylie Avenue around 10:40 p.m.
Officers located an unresponsive male victim with a gunshot wound to the head outside Tim's Bar.
Medics transported him to the hospital in critical condition where he was later pronounced deceased.
Detectives from Major Crimes and the Crime Scene Unit are processing evidence at the scene.
One male was taken to police headquarters for questioning.
The investigation is ongoing.