Pittsburgh Police, Fire, and EMS responded to N. Lang Avenue and Upland Street for a single vehicle collision just after 8:15 p.m.
When first responders arrived on scene they observed a vehicle that had caught fire after it sheared a telephone pole and then struck the front of a house.
Firefighters from Engine 15 responded to extinguish the fire.
Medics transported two female victims to the hospital in stable condition with minor injuries. One suffered a leg injury, the other had a cut to the head.
Police are investigating.