Pittsburgh EMS, Fire, and Police responded to a multi-vehicle collision on the West End Bridge around 7:30 p.m.
When first responders arrived, they located the motorcyclist down on the street. Two other vehicle were also involved in the collision.
The male cyclist was pronounced deceased by medics at the scene. He was wearing a helmet at the time of the collision.
The drivers and passengers in the sedans were not injured and remained on the scene.
The Collision Investigation Unit are investigating to determine the cause.
The bridge will reopen once the on-scene investigation has concluded.