Pittsburgh Bureau of Police officers from Zone 5 responded to a ShotSpotter notification of multiple gunshots in the 400 block of Larimer Avenue around 4:30 p.m.
Multiple 911 calls reporting gunfire with victims were also received.
Police and EMS found a female victim with a gunshot wound to her leg near the scene of the shooting, and a male victim with a gunshot wound to the face on the 100 block of Mayflower Street.
EMS transported both victims to a local hospital in serious condition.
No arrests have been made. Police are investigating.